Histology and Cytology Theory Paper

  1. The fixative of choice for cytological smears is:

A) Isopropyl alcohol

b) Picric acid

c) 95% Ethanol

d) 10% formal saline


2. Tissue processing by use of molten paraffin wax involves the following procedures:

a) Infiltration

b) Hydration

c) Dehydration

d) Clearing


3. Xylene, a clearing agent is:

a) Miscible with water

b) Miscible with alcohol

c) Miscible with d.p.x

d) Miscible with both alcohol and d.p.x


4. The following microtome uses knives made of stainless steel except:

a) Rotary

b) Base sledge

c) Freezing

d) Ultra-thin


5. The following are histological special staining except:

a) Haematoxylin and eosin

b) Giemsa

c) Ziel-Nielsen

d) Gram’s


6. In staining, bluing is achieved by the use of:

a) Strong acids

b) Weak acids

c) Basic solutions

d) Hydrochloric acid


7. The following are true of calcium ions except:

a) Are radio-opaque

b) Are positively charged

c) Are attracted to the cathode

d) Are attracted to the anode



8. The following is not true of mitosis

a) Has prophase as its 1st stage

b) Has interphase as its 1st stage

c) It’s affected by radiological levels

d) It’s affected by excessive heat


9. Microtome knives are identified by their profiles. Profile A is always:

a) Biconcave

b) Plane concave

c) Plain wedge

d) Tool edge


10. The following are artifact pigments except:

a) Carbon pigments

b) Formalin pigments

c) Mercuric chloride pigments

d) Chrome pigments


11. The following are endogenous pigments except:

a) Formalin

b) Melanin

c) Haemosiderin

d) Calcium


12. Which of the following natural dyes is obtained from a flower Crocus salivas?

a) Saffron

b) Lithmus

c) Carmine

d) Orcein


13. The following are Romanowski dyes except:

a) Leishman stain

b) May-Grunwald stain

c) Giemsa stain

d) Gram stain


14. Fixation can be influenced by:

a) pH

b) Type of tissue

c) Temperature

d) Light

e) Concentration of cells


15. Simple fixatives include:

a) Schaudinn’s fluid

b) Acetic acid

c) Bouin’s acid

d) Picric acid

e) Carnoy’s fluid


16. The following structure is found in the kidney:

a) Sweat glands

b) Epidermis

c) Glomeruli

d) Bronchioles

e) Villi


17. Which of the following requires decalcification?

a) Cartilage

b) Tuberculous lymph node

c) liver

d) Skin

e) Sole biopsy


18. Hypercalcemia is associated with the following:-

a) Hypoparathyroidism

b) Haemochromatosis

c) Hypomagnesaemia

d) Osteomyelitis

e) Infectious arthritis


  1. Formaldehyde causes the following:-

a) Contact dermatitis

b) Cancer

c) Burns

d) Flu

e). Blindness


  1. Most specimens processed in histopathology laboratory are obtained from:-

a) Theatres

b) Museums

c) Postmortems

d) Wards

e) Surgical clinics