Hematology Theory Paper

Q.1.   The biological functions of the FC fragment is/are:

a) Antigen binding

b) Complement fixation

c) Antibody binding

d) Placental transfer

e) Production of antibodies


Q.2.   Blood group specific substances are:

a) Alcohol soluble

b) Water-soluble

c) Haptens

d) Amino acid with mucopolysaccharide fraction

e) Antibodies of high specificity


Q.3.   An offspring of genotype rr will give a positive reaction with the following antibodies:

a) Anti Rho

b) Anti rh1

c) Anti hr1

d) Anti hr11

e) Anti rh1


Q.4.   The following are some of the ABO grouping panel cells:

a) A cells

b) O cells

c) Dĉê cells

d) DCE cells

e) Cells


Q.5.   The following reagents must be added to 22% to prevent over polymerization:

a) Calcium chloride

b) Caprylate

c) Sodium alginate

d) 1% Sodium azide

e) Ammonium Sulphate


Q.6.   Zeta potential is reduced by:

a) De-ionized water

b) Centrifugation

c) 22% bovine albumin

d) Enzymes

e) Sodium Sulphate


Q.7.   Which of the following fixes complement?

a) 1gG

b) 1gA

c) 1gM

d) 1gD

e) 1gE


Q.8.   Anti-Human serum specific for complement component is produced by injecting rabbits with purified human:

a) Beta globulin

b) Alpha globulin

c) Gamma globulin

d) Delta

e) Mu


Q.9.   The following are some of the characteristics of a natural antibody:

a) Incomplete antibodies

b) Complete antibodies

c) 1gM

d) Are usually 250Ao in length

e) Crosses the placental barrier


Q.10. Which of the following is/are adjuvants?

a) 10% formalin

b) 4% Sodium alginate

c) Freund’s adjuvant

d) Liss

e) Caprylate


Q.11. The low-grade Du red cells:

a) Can be detected using 1gM anti-D

b) Can falsely be typed as Rhesus negative

c) Can be detected using anti-human globulin (AHG) technique

d) Can be transfused to Rhesus negative individuals safely

e) Is considered as Rhesus negative


Q.12. A major X-match will not:

a) Raise the Hb-level of the patient

b) Prevent immunization

c) Detect ABO errors

d) Detect errors of documentation

e) Be done during an emergency


Q.13. If the phenotype is DCCEE what are the probable genotype?

a) DCê/dĉê

b) DCE/Dce


d) Dĉê/dĉê

e) DĉE/Dce


Q.14. If a parent is a homozygous AA and the other is OO, their offspring will be blood group:

a) A

b) B

c) O

d) AB

e) AO


Q.15. Red blood cells antigens are made up of:

a) Polysaccharide

b) Amino acid

c) Peptides

d) Enzymes

e) Mineral salts


Q.16. In ABO blood group system there are:

a) 4 genotypes

b) 4 phenotypes

c) 6 genotypes

d) 6 phenotypes

e) 8 genotypes


Q.17. The following are Rhesus grouping techniques:

a) ABO Forward grouping

b) ABO reverse grouping

c) Antibody Screening Test

d) Direct Coomb’s test

e) Station Sandwich method


Q.18. The fisher-race gene complex DCê is equivalent to:

a) Ry

b) Ro

c) R1

d) R

e) Rz


Q.19. Rhesus antibodies:

a) Occur naturally

b) Are IgM

c) Are complete antibodies

d) Belong to IgA class

e) Belong to IgG class


Q.20. Plasma is not preferred in blood transfusion for serological tests because:

a) Plasma contains complement components

b) Calcium and Magnesium ions have been removed

c) Fibrinogen is present

d) Plasma forms fibrin clots

e) It gives a positive reaction in hemolysis


Q.21. Complement component can be obtained from:

a) Guinea pig fresh serum

b) Birds fresh serum

c) Reptiles fresh serum

d) Plant

e) Rabbits fresh serum


Q.22. If Beta and gamma anti-human serum is sourced from one colony it is said to be:

a) Monoclonal

b) Polyspecific

c) Polyclonal

d) Monologues

e) Monospecific


Q.23. The immunoglobulins that are capable of crossing the placental barrier are:

a) 1gM

b) 1gG

c) React optimally at 37°C

d) React optimally at R.T

e) 1gD