Clinical Chemistry Theory Paper

1 Glucose working standards are preserved in

a) Benzoic Acid

b) Hydrochloric acid

c) Sodium fluoride

d) Chloroform

d) Formaldehyde


2. Conjugated bilirubin is

a) Bound to Albumin

b) Reduced bilirubin

c) Bilirubin glucuronide

d) Less-toxic

e) Toxic


3. Uric acid forms as an end product of

a) Purine metabolism

b) Pyrimidine metabolism

c) Nucleoprotein metabolism

d) Urea metabolism

c) Ammonia metabolism


4. The law that relates transmitted light to the concentration of the solution is

a) Lamberts’ law

b) Beers’ law

c) Charles’ law

d) Daltons’ law

e) Boyles’ law


5. Quality Control (QC) in chemical Laboratory

a) should be done once a month

b) should be done regularly

c) d) should not be performed

d) starts when the specimen is being taken

e) not important


6. The buffer in alkaline Phosphatase estimation is

a) Phenyl Phosphate

b) Bicarbonate/Phosphate

c) Carbonate /bicarbonate

d) 4-aminophenazone

e) Phenol


7. Serum glutamate-Pyruvate acid transaminase (SGPT) has the substrate as

a) Alanine

b) Pyruvate

c) Aspartate

d) Oxaloacetate

e) Glutamate




8. CSF normal Protein range is

a) 15 – 40 gm%

b) 15-40 mg%

c) 015 – 0.04 g/L

d) 15-0.4 mg%

e) 15-0.4 g/L


9. A molar solution contains: –

a) One mole /litre of solvent

b) One gram molecular weight of solute/litre of solution

c) One mole /litre of solvent

d) The gram molecular weight of solvent/litre of solute

e) One mole solute/litre of solution


10. During the detection of pentoses, the reagent used: –

a) Has resorcinol

b) Gives a red colour when positive

c) Has orcinol

d) Has hydrochloric acid

e) Yields a blue colour when positive


11. To make a buffer solution one needs: –

a) a weak acid and conjugate salt

b) strong acid and weak base

c) weak acid and conjugate acid

d) strong base and conjugate salt

e) strong acid and conjugate base


12. The non-sugar reducing substances which can be detected in urine include:-

a) Gluconic acid

b) creatinine

c) Urea

d) Uric acid

e) Diacetic acid


13. The indirect reacting bilirubin is:-

a) Water-insoluble

b) Water-soluble

c) Alcohol insoluble

d) Toxic

e) Conjugated


14. Gerhardt’s reagent detects the presence of:-

a) Acetic acid

b) Dimethylketone

c) Acetone

d) Acetoacetic acid

e) Diacetic acid


15. Complexing bilirubin and diazo reagent yields:-

a) Bilirubin glucuronide

b) Reduced bilirubin

c) Diazotised sulphanilic acid

d) Biliverdin

e) Azobilirubin


16. A strong base has a pH of 11.8 what is its molarity:-

a) 03

b) 015

c) 2

d) 018

e) 006


17. If 20 ml of 80 mg/dl glucose standard is diluted to one litre, the resulting solution would be:-

a) 16 mg/dl

b) 6 mg/dl

c) 6 mg/l

d) 16 g/dl

e) 16 mg/l


18. Total proteins in CSF may be estimated using

a) Maulemann’s reagent

b) Biuret reagent

c) 6% sodium sulphate

d) Pandy’s reagent

e) 3% trichloroacetic acid


19. Buffering capacity:-

a) Depends on the salts

b) Is best above pK of the buffer

c) Is best near pK of buffer

d) Is best below pK of the buffer

e) Depends on the acid


20. In the indirect pregnancy test, agglutination is interpreted as

a) Reactive

b) Non-reactive

c) Not pregnant

d) False positive

e) Pregnant