Clinical Chemistry Theory paper

  1. Yeast fermentation will detect which of these sugars

a) Arabinose

b) Fructose

c) Ribose

d) Cellulose

e) Sucrose


2. Glycosuria without Hyperglycaemia in oral glucose Tolerance Test detects

a) Renal Threshold

b) Diabetes mellitus

c) Diabetes inspidus

d) Renal glycosuria

e) Flat diabetic curve


3. The reaction of a Carboxylic acid and an alcohol is

a) Polymerization

b) Saponification

c) Peptide bonding

d) Glycosidic bonding

e) Esterification


4. Commonly used chromogens include

a) Arsenomolybdic acid

b) Hydrogen peroxide

c) Gluconic Acid

d) Ortho-tolidine

e) Guaiacum


5. The condition whereby enzymes act best is known as

a) Catalytic activity

b) Optimum activity

c) Maximum activity

d) Minimum activity

e) Acidosis


6. On decarboxylation, acetoacetic acid yields:

a) Acetone

b) Aldehyde

c) Oxaloacetate

d) Beta-hydroxybutyric acid

er) A ketone


7. Urinometer is used for the estimation of

a) SG

b) Urea

c)_ Albumin

d) Protein

e) Glucose


8. Both DNA and RNA contain Pyrimidine bases called

a) Guanine

b) Xanthine

c) Cytosine

d) Thymine

e) Adenine


9. Bence-Jones protein in urine can be tested by

a) Sulphosalysalic acid

b) Nitric acid test (Hellers)

c) Bradshaw’s test

d) Electrophoresis

e) Gmelin’s test


10. Calculate the Optical Density given percentage transmittance to be 40%

a) 2

b) 4

c) 5

d) 6

e) 3


11. Glucose working standards is always preserved in

a) Benzoic Acid

b) Hydrochloric acid

c) Sodium fluoride

d) Chloroform

e) Diaphenyl Carbazone


12. Conjugated bilirubin is

a) Bound to Albumin

b) Reduced bilirubin

d) Bilirubin glucoronide

d) Less-toxic

e) Toxic


13. Renal Amino-aciduria is a defect due to

a) Tubular reabsorption

b) Urinary tract obstruction

c) Liver diseases

d) Glomerular filtration

e) Intestinal obstruction


14. Which of these are Purine Bases?

a) Arginine

b) Adenosine

c) Guanine

d) Cytosine

e) Thymine


15. Substances that dissolve to form suspensions

a) Crystalloids

b) Suspensoids

c) Emulsoids

d) Colloids

e) Dialysis


16. During the use of a PH meter, the Silver/Silver Chloride is

a) gravimetric analysis

b) standard PH electrode

c) reference electrode

d) potentiometric

e) equivalent electrode


17. Uric acid forms as an end product of

a) Purine metabolism

b) Protein metabolism

c) Nucleoprotein metabolism

d) Urea metabolism

e) Ammonia metabolism


18. The law that relates transmitted light with the thickness of the solution is

a)Lamberts’ law

b) Beers’ law

c) Charles’ law

d) Dattons’ law

e) Boyles’ law


19. Augmented histamine test in gastric juice analysis

a) Is done when the Patient has fasted

b) Is done when the Patient has not fasted

c) Antihistamine given first

d) Is done to defect renal defect

e) Uses dilute alcohol for stimulation


20. Quality Control (QC) in chemical Laboratory

a) should be done once a month

b) should be done regularly

c) should not be performed

d) starts when the specimen is being taken

e) not important



21. 2Bicarbonate is usually estimated in the laboratory by

a)Flame photometry

b) Colorimetry

c) Titration

d) Chromatography

e) Neutralization


22. The buffer in alkaline Phosphatase estimation is

a) Phenyl Phosphate

b) Bicarbonate/Phosphate

c) Carbonate /bicarbonate

d) 4-aminophenazone

e) Phenol


23. When urea is heated above the melting point (over 180oC)

a) Citrulline is formed

b) Biuret is formed

c) Ammonia is formed

d) Carbon dioxide is formed

e) Urochrome is formed


24. Which of these reagents are used in Cholesterol Estimation?

a) Hydrochloric acid

b) Methanol

c) Chloroform

d) Nitric acid

e) Acetic anhydride/Sulphuric acid


25. Serum glutamate-Pyruvate acid transaminase (SGPT) has the substrate as

a) Alanine

b) Pyruvate

c) Aspirate

d) Beta Oxaloacetate

e) Glutamic acid


26. Amylase always act on starch and the endpoint can be determined by

a) Potassium Iodide

b) Iodine

c) Fluorine

d) Bromine

e) Chlorine


27. CSF normal Protein range is

a) 6-8gm%

b) 15-40mg%

c) 3-4mg%

d) 15-0.4mg%

e) 15-0.4gm/L