Clinical Chemistry Theory Paper

Q1.      The PH of a solution is given as 6, what is the concentration of a hydroxyl ion (OH-)?

a) 000001

b) 106

c) 10-6

d) 10-8

e) 108


Q2.      The percentage transmittance of solution who’s OD = 0.7 is:

a) 20%

b) 40%

c) 30%

d) 50%

e) 10%


Q3.      10 ml of 0.1 M NaOH neutralizes 5 ml of HCl the concentration of the acid is therefore:

a) 2 M

b) 2 M

c) 1 M

d) 02 M

e) 5 M


Q4.      Water, which is prepared by still apparatus, is:

a) Sterile but has soluble salts

b) Sterile and free from water-soluble salts

c) Not sterile but free from soluble salts

d) Sterile and free from insoluble salts.

e) Sterile only.


Q5.      Inflame photometry, the specimen is sprayed into the burner by:

a) Monochromator

b) Photodetector

c) Nebulizer

d) Capillary tube

e) Atomizer


Q6.      Thin-layer chromatography techniques are based on which principles:

a) Partition and Adsorption

b) Partition and Gel-filtration

c) Gel-filtration and ion-exchange

d) Absorption and Gel-filtration

e) Absorption and Ion-exchange


Q7.      Tetrabromphenol blue is an indicator used in:

a) Clinitest

b) Clinistix

c) Albustix

d) Ictostix

e) Azostix


Q8.      To make 8 ml of a 1 in 200 serum dilution, you need:

a) 1 ml of serum

b) 04 ml of serum

c) 8 ml of serum

d) 4 ml of serum

e) 02 ml of serum


Q9.      In pre-hepatic jaundice, indirect Bilirubin in serum is:

a) Low

b) Normal

c) High

d) Nil

e) Not affected


Q10.    In Schales and Schales method for Cl ion determination, the indicator used in the titration is:

a) Diphenyl Carbazone

b) Phenolphthalein

c) Phenol red

d) Methyl red

e) Neutral red


Q11.    The common test/s for detecting glucose, fructose, and lactose in urine is/are:

a) Clinistix

b) Methylamine

c) Osazone test

d) Clinitest

e) Benedict reagent


Q12.    The following are ketone bodies formed as a result of the loss of carbon dioxide?

a) Aceto-acetic acid

b) Acetone

c) Beta-hydroxybutyric acid

d) Β – hydroxybutyric acid

e) Ketones


Q13.    Phenistix is a paper strip for detecting:

(a) Ketonemia

b) Salicylates and phenyl pyruvic acid

(c) Beta-hydroxybutyric acid and Salicylates

d) Acetone and Acetoacetic acid

e) Acetone and β- hydroxybutyric acid


Q14.    Proteins are coagulated by heat in a slightly acid medium. Which acid is commonly used?

a) 5% acetic acid

b) 5% aceto-acetic acid

c) 5% sulfosalicylic acid

d) 3% sulfosalicylic acid

e) nitric acid


Q15.    Eibach’s test is used to detect:

a) Protein in urine

b) Glucose in urine

c) Ketones in urine

d) Bence-Junes protein

e) Salicylates in urine


Q16.    Which of these products is/are structurally the same as stercobilinogen?

a) Stercobilin

b) Urobilinogen

c) Indirect bilirubin

d) Direct bilirubin

e) Urobilin


Q17.    Which of the following are characteristics of direct bilirubin, which assist in its estimation in serum?

a) Conjugated

b) Non-toxicity

c) Water solubility

d) Alcohol insoluble

e) Alcohol soluble


Q18.    Liebermann – Burchard method measures:-


b) Cholesterol

c) Lipids

d) Steroids

e) Proteins


Q19.    Which of the following hormones are involved in gastric juice secretion?

a) Rennin

b) Pepsin

c) Sucrose

d) Trypsin

e) Insulin


Q20.    In paper electrophoresis, the serum protein is usually presented as:

a) 4 bands

b) 5 bands

c) 6 bands

d) 7 bands

e) 8 bands


Q21.    Lambert’s Law relates transmitted light from a colored solution to:

a) Thickness of the solution

b) Concentration of the solution

c) Extinction of the solution

d) Blank of the solution

e) Specific gravity of the solution


Q22.    Diazo reagent is composed of:

a) Sulphuric acid

b) Hydrochloric acid

c) Sodium Nitrate

d) 4-aminophenazone

e) sulphosalicyclic acid


Q23.    Mohr’s indicator is:

a) Ferric chloride

b) Ferric Alum

c) Potassium Dichromate

d) Potassium chromate

e) Ammonium thiocyanate


Q24.    The major extracellular anion of the body is/are:

a) Chloride

b) Potassium

c) Sodium

d) Bicarbonates

e) Calcium


Q25.    The clinical condition caused by Hyperventilation is:

a) Metabolic alkalosis

b) Respiratory acidosis

c) Respiratory alkalosis

d) Hyperglycaemia


Q26.    Serum/plasma bicarbonate may be estimated by:

a) Titrimetric method

b) Turbidimetric method

c) Colorimetric method

d) Enzymatic method

e) Photometric method


Q27.    Amylase estimation may be used in the diagnosis of:

a) Acute pancreatitis

b) Nephritic syndrome

c) Salivary gland disorders

d) Gastric disorders

e) Hepatitis


Q28.    The two diagnostically useful transaminases are:

a) Glutamate Oxaloacetate transaminase

b) Glutamate Pyruvate transaminase

c) Oxoglutarate Pyruvate

d) Aspartate aminotransferase

e) Alanine amino-Oxaloacetate


Q29.    When glucose and copper II solution react in an alkaline medium:

a) The glucose is oxidized

b) The copper II ions are reduced

c) The glucose is reduced

d) The glucose becomes an alkali

e) A black/blue color develops


Q30.    Uric acid is the end product of:

a) Nucleic acid metabolism

b) Rbcs metabolism

c) Protein metabolism

d) Purine metabolism

e) Wbc metabolism


Q31.    Heller’s test utilizes:

a) HCl

b) H2SO4

c) HNO3


e) Ammonia


Q32.    Reduction of biliverdin yields:

a) Indirect Bilirubin

b) Direct Bilirubin

c) Urobilinogen

d) Stercobilinogen

e) Glucoronic acid