Clinical Chemistry Theory Paper

Q.1.     Parenteral stimulants include:

a) Alcohol

b) Insulin

c) Milk less tea

d) Gruel

e) Pentagastrin


Q.2.     Which of the following substances indicate physiological disorder if found in gastric juice

a) Hydrogen ions

b) Hydroxyl ions

c) Mucus

d) Bilirubin

e) Trypsinogen


Q.3.     The process of urea hydrolysis can be affected by:

a) Alcohol

b) Bicarbonates

c) Phosphates

d) Urease enzyme

e) Metallic halides


Q.4.     Biuret reaction involves coordination complex of copper ions with:

a) 2 – CaOH

b) 2 – OH

c) 2 – C = O

d) 2 – CONH

e) 2 – NH2


Q.5.     The pH of 0.001 HCl is:

a) 2

b) 3

c) 1

d) 3

e) More than 2


Q.6.     Ion-free pure water may be prepared by:

a) Refrigeration

b) Distillation

c) De-ionisation

d) Decantation

e) Electrolysis


Q.7.     The filters below were used to determine the optical densities of a coloured solution.  The respective OD values were recorded accordingly.  The best filter for that solution is:

a) Blue filter which gave O.D.   = 0.3

b) Green filter which gave O.D.   = 0.4

c) Red filter which gave O.D.   = 0.5

d) Blue/green filter which gave O.D.   = 0.6

e) Yellow filter which gave O.D.   = 0.7


Q.8.     The incomplete metabolism of fatty acids yields:

a) Acetoacetic acid

b) Urea

c) Oxaloacetate

d) Salicylates

e) Uric acid


Q.9.     None-functional plasma enzymes include:

a) Amylase

b) Prothrombin

c) Coagulation factor V

d) Coagulation factor VII

e) Prostatic acid phosphatase


Q.10.   The following is/are true about disaccharides:

a) Do not form crystalline solids

b) Are soluble in water

c) Are insoluble in water

d) Are hydrolyzed by acids to form monosaccharide

e) Are not hydrolyzed by acids


Q.11.   The following is/are apparatus used in specific gravity determination:

a) Refractometer

b) Weighing balance

c) Colorimeter

d) Spectrophotometer

e) Absorptometer


Q.12.   The main natural pathways of gastric juice stimulation involve:

a) Dilute alcohol

b) Tea without milk

c) Gastrin

d) Oatmeal

e) Vagus nerve


Q.13.   The following substances may be tested for in urine in a suspected case of obstructive jaundice:

a) Urea

b) Sodium ions

c) Chloride ions

d) Bile salts

e) Bilirubin


Q.14.   Chemical reduction process involves:

a) Electron gain

b) Loss of electrons

c) Loss of water molecule (H2O)

d) Loss of hydrogen molecules

e) Gain of water molecules


Q.15.   Simple lipids are derived from the following classes of organic compounds:

a) Acetone

b) Alcohol

c) Carboxylic acids

d) Esters

e) Amines


Q.16.   Reduced glucose tolerance results:

a) Hyperglycaemia

b) Hypoglycemia

c) Diabetes mellitus

d) Renal glycosuria

e) Reduced renal threshold


Q.17.   In Serum electrophoresis, Bence Jones proteins is found between:

a) Alpha 1 globulin and albumin

b) Alpha 2 globulin and Beta globulin

c) Beta globulin and gamma globulin

d) Cathode and gamma globulin

e) Anode and alpha globulin


Q.18.   In the presence of alkaline and heat, some sugars undergo re-arrangement reaction, this is the basis of:

a) Methylamine test

b) Benedict’s test

c) Seliwanoff’s test

d) Bial’s test

e) Osazone


Q.19.   Ammonia gas couples with phenol-hypochlorite in the presence of sodium Nitroprusside forming blue color; this is useful for the determination of:


Complex protein


Peptide bonds



Q.20.   Which of the following instruments use a photocell?

a) Ph meter

b) Colorimeter

c) Urinometer

d) Flame photometer

e) Refractometer


Q.21.   In pre-hepatic jaundice, indirect bilirubin in plasma is:

a) Low

b) Normal

c) High

d) Nil

e) Below normal


Q.22.   Urine pH measurement is externally influenced by:

a) Humidity

b) Pressure

c) Uncontrolled diabetes mellitus

d) Loss of CO2

e) Temperature


Q.23.   The following methods can be used in the detection of hemoglobinuria:

a) Microscopy

b) Spectroscopy

c) Ph meter reading

d) Refractometry

e) Haemastin


Q.24.   The renal threshold for urea is:

a) 1 mmol/L

b) 2 mmol/L

c) 0 mmol/L

d) 3 mmol/L

e) 4 mmol/L


Q.25.   The relationship between transmitted light and the thickness of curette is described by:

a) Lamberts law

b) Beers law

c) Beer – lamberts law

d) Law of mess action

e) Law of definite proportion


Q.26.   Which of the following tests can be used to quantitative protein in urine?

a) Gerhardt’s

b) 3% S.S.A.

c) Eibach’s tube

d) Phenistix

e) Occult test