Clinical Chemistry Theory Paper

  1. Van der Waals forces are applicable in:

(a)        Chromatography

(b)       Electrophoresis

(c)        Flame photometry

(d)       Atomic absorptiometry

(e)        Get titration


2. In indirect pregnancy test, Agglutination is:

(a)        Positive test

(b)       Negative test

(c)        False-negative test

(d)       False-positive

(e)        Non- confirmatory


3. Bial’s reagent for pentoses consists of the following:

(a)        Conc. sulphuric Acid

(b)       Conc. Nitric Acid

(c)        Orcinol

(d)       Conc. hydrochloric Acid

(e)        10% Ferric chloride


4. Osazones reagent consists of the following chemicals:

(a)        Sodium acetate

(b)       Phenyl hydrazine hydrochloride

(c)        Zinc acetate

(d)       Sodium chloride

(e)        Mercuric chloride


5. The suitable method for detecting urinary urea is:

(a)        Urastrat method

(b)       Berthelot’s method

(c)        Azostix

(d)       Diacetyl monoxime

(e)        Hypobromite method


6. Bradshaw’s test detects:

(a)        Pentoses

(b)       Proteins

(c)        Reducing substances

(d)       Bence Jones proteins

(e)        Gamma globulins




7. Conversion of acetoacetate to beta-hydroxybutyric acid is a:

(a)        Reduction process

(b)       Oxidation process

(c)        Decarboxylation process

(d)       Redox process

(e)        De- acylation process


8. Which of the following is/are confirmatory test(s) for Bence Jones proteins?

(a)        Bradshaw’s test

(b)       Layering method

(c)        Boiling method

(d)       Electrophoresis

(e)        Sulphosalicyclic Acid


9. Which of the following is/are associated with Ketonuria?

a) Diabetes Ketosis

b) Fasting

c) Strict protein diet intake

d) High carbohydrate

e) Prolonged dehydration


10. 10.0 ml of 0.4 M HCl will react with how many ml of 0.I M NaOH?

a) 4 litres

b) 400 ml

c) 40 ml

d) 4 ml

e) 04 litres


11. The optimum PH for acid phosphate estimation is:

a) 9

b) 0

c) 0

d) 8

e) 1


12. Which of the following substance will be reduced in plasma in liver failure?

(a)        Albumin

(b)       Urea

(c)        Creatinine

(d)       Uric acid

(e)        Transaminase


13. Which of the following substance/s can be used as a measure of Glomerular

filtration rate?

a) Insulin

b) Creatinine

c) Glucose

d) Uric acid

e) Ammonia


14. Seliwanoff’s test detects

a) Frutosuria

b) Pentosuria

c) Ketonuria

d) Glucosuria

e) Proteinuria


15. The indicator used in chloride estimation by Schales and Schales method is:

(a)        Diphenyl Carbazone

(b)       Potassium dichromate

(c)        Phenol red

(d)       Methyl red

(e)        Methyl orange


16. Dubosq is associated with:

(a)        Filtration

(b)       Distillation

(c)        Flame photometry

(d)       Atomic absorption

(e)        Colorimetry


17. Which of the following urea estimation method does not utilise urease enzyme?

(a)        Nesslerization method

(b)     Berthelot’s method

(c)        Azostix method

(d)       Diacetyl monoxime method

(e)        Urastrat method


18. The importance of Methanol in Bilirubin estimation is to:

(a)        Convert indirect bilirubin to direct bilirubin

(b)       Provide an acid medium

(c)        Provide a suitable pH

(d)       Combines with the diazo reagent

(e)        Promote colour development


19. Which of the following vitamins is/are fat-soluble?

(a)        K

(b)       Thiamine

(c)        A

(d)       C

(e)        B12


20. Achlorhydria is associated with:

(a)       Pernicious anaemia

(b)      Lack of vitamin B12

(c)       Vitamin C

(d)       Lack of intrinsic factor

(e)        Lack of vitamin C


21. Which of the following is/are parenteral stimulants?

a) Dilute alcohol

b) Gruel

c) Pentagastrin

d) Tea without milk

e) Insulin


22. Colourimetry is associated with?

a) Thickness of coloured solution

b) Intensity of coloured solutions

c) Flame absorptiometry

d) Bear – Lambert’s law

e) Flame photometry


23. Glucosuria could be due to:

a) Diabetes mellitus

b) Diabetes inspidus

c) Low renal threshold

d) High carbohydrate diet

e) High renal threshold


24. Which of the following are causes of a false occult positive test?

a) Parasitic infection

b) Ulcers

c) Cancers

d) Presence of iron on glassware

e) Not abstaining from meat prior to testing


25. Which of the following is /are a cause of high specific gravity of urine?

a) Diabetes inspidus

b) Proteinuria

c) Ketonuria

d) Polyuria

e) Oliguria


26. Which of the following can be a cause of acid urine excretion?

a) Alkalosis

b) Diabetes inspidus

c) Fever

d) Hyperventilation

e) Asthma