Clinical Chemistry Theory Paper


  1. Bence Jones proteins can be detected by

a) Concentrated hydrochloric acid

b) 33% Diacetic acid

c) Urastrat strip

d)Hay’s test

e) 3% TCA


  1. The final colour of urine is due to

a) Ammonia

b) Creatinine

c) Creatine

d) Urochrome

e) Urea


  1. The following are Rothera’s reagents

a) Benedict’s reagent

b) Sodium Sulphate

c) Hydrochloric acid

d) Sodium nitroprusside

e) Ammonium Sulphate


  1. Increase in blood glucose is known as

a) Hypoglycaemia

b) Diabetes Inspidus

c) Hyperglycaemia

d) Acidaemia

e) Diabetes mellitus


  1. The following are serum protein fraction/s

a) Amylase

b) Albumin

c) Globulin

d) Lipid

e) Fibrinogen


  1. Urine is formed using the following principles

a) Absorption

b) Adsorption

c) Simple filtration

d) Krebs’s cycle

e) Selective reabsorption


  1. 50% transmittance of a solution give an OD of

a) 5

b) 4

c) 3

d) 2

e) 1


  1. The PH of a 0.0001M HCL is

a) 0

b) 0

c) 0

d) 0

e) 0


  1. The Lieberman-Burchard reaction is associated with

a) Cholesterol estimation

b) Bilirubin determination

c) Uric acid estimation

d) Protein estimation

e) Acid Phosphatase


  1. Bloor’s reagent is used in the estimation of

a) Blood sugar

b) Cholesterol

c) Uric acid

d) Bilirubin

d) Lipids


  1. The surface tension of urine is lowered by

a) Amino acids

b) Bile salts


d) Glucose

e) Chloride


  1. Optical Density is calculated by the formulae

a) 2 + log %T

b) 2 – log %T

c) Log T – 2

d) Log T

e) Log 1 – 00 – Log%T


  1. The common principles in Chromatography include:

a) Adsorption


c) Absorption

d) Malabsorption

e) Saponification


  1. In pre-hepatic jaundice, indirect bilirubin is

a) Low

b) Normal

c) High

d) Nil

e) Above normal


  1. Uric acid may increase abnormally in the plasma due to

a) Renal fructose


c) Ulcers

d) Diarrhoea

e) Intake of purine


  1. Acid/Base titrations are based on

a) Reduction

b) Neutralization

c) Oxidation

d) Redox

e) Precipitation


  1. Lambert’s law relates transmitted light of a coloured solution to

a) Thickness of the solution

b) Concentration of the solution

c) Extinction

d) Blank

e) Specific gravity


  1. Which of the following is true about the indirect bilirubin

a) Water soluble

b) Conjugated

c) Non-toxic

d) Protein bound

e) Alcohol soluble


  1. Bial’s test will be negative with the following

a) Sucrose

b) Pentose

c) Xylose

d) Fucose

e) Glucose


  1. A fasting blood glucose level of 14.0 mmol/L is

a) Above normal

b) 140mg/dl

c) Suggestive of diabetes mellitus

d) Below normal

e) Considered normal


  1. Proteins can be semi-quantitated in urine using

a) Eibach’s tube

b) Gerhardt’s reagent

c) Albustix

d) Hay’s test

e) Acetic acid reagent


  1. Indicators are either …… or …

a) Buffers

b) Strong acids

c) Weak bases

d) Weak acids

e) Strong bases


  1. The normal concentration of blood glucose by oxidase method under fasting condition is

a) 50 – 150 mg%

b) 50 – 90mg%

c) 80-120mg%

d) 80-180mg%

e) 8-5.0mmols/L


  1. Some of the common urine preservatives include

a) Hypochlorite

b) Dichromate

c) Ammonia

d) HC

le) Thymol


  1. In paper chromatography, the stationary phase is


b) Solvent molecules

c) Urate molecules

d) Elutanant

e) Non-polar


  1. A carcinogenic chromogen system is

a) O – toluidine

b) Arsenomolybdic acid

c) Phosphomocybdic acid

d) Gluconic acid

e) Guaiacum


  1. Bence Jones proteins can be detected by

a) Concentrated hydrochloric acid

b) 33% Diacetic acid

c) Urastrat strip

d) Hay’s test

e) 3% TCA