Empowering MLSTs
Relevant immunological information to a medical laboratory scientist and technologist
T- Lymphocytes is a major class of lymphocytes whose precursors arise from the bone marrow then migrate and mature in the thymus of which they derive their name (Thymus derived lymphocytes). They are divided into functionally distinct populations which are T- helper cells (CD4+), cytotoxic cells (CD8+) and the T-regulatory cells (CD4+).
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The cytokines that play a major role in the mediation of natural immunity include:
Antibodies are groups of proteins composed of between 82 to 96% polypeptide and 4 to 18% carbohydrate. They are present in the serum and tissue fluids of vertebrates. Some are curried on the cell surface where they act as receptors while others are free in the blood or lymph, referred to as the antibodies.
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The major characteristics of acquired immunity include memory, specificity and recognition which makes it invaluable in protecting against recurrent infections.
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Cytokine is a general name meaning ‘cell produce’. Cytokines are therefore small secreted proteins that mediate and regulate immunity, inflammation, and hematopoiesis normally produced due to an immune stimulus.
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The process of Phagocytosis involves taking the particulate matter into a cell. Different types of cells can phagocytose at times, however, there are specialized phagocytic cells in the body of mammals namely the large macrophages and the smaller polymorphonuclear leukocytes
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