Blood Transfusion Theory Paper


Q.1.   The cells from the following blood group will not react with Anti-A, Anti-B and Anti-H:

a) O cells

b) A cells

c) B cells

d) Oh cells

e) Bombay phenotype


Q.2.   If the mother is A2 A2 and the is father is A1 A2 which of the following is/are the probable genotypes of the offspring:

a) A2 A2

b) A1 A1

c) A2 B

d) A1 A2

e) A1 O


Q.3.   The following are indirect antiglobulin techniques except:

a) Major cross-match

b) Reverse grouping

c) Du test

d) Antibody screening

e) Minor crossmatch


Q.4.   Anti – H will react strongly with the following cells:

a) Oh

b) O

c) A2 B

d) A1 B

e) B


Q.5.   Lectin Anti – A can be prepared from:

a) Iberis amara

b) Vicia graminea

c) Ulex eruopeus

d) Dolichous biflorous

Lotus tetragonolobus


Q.6.   Rh-null phenotype occurs as a result of:

a) Genetic mutation

b) Suppressor gene X° r

c) Normal gene X1r

d) Recessive gene d

e) Silent gene h


Q.7.   The Panagglutination due to the bacterial alteration of red blood cells is also known as:

a) Raynaud’s phenomenon

b) Robinson phenomenon

c) Thomsen phenomenon

d) Prozone phenomenon

e) Mutahasi-Ogata phenomenon


Q.8.   The Weiner antigens Rho and Rh1 are equivalent to which Fisher-Race Complex:

a) DCE

b) DCe

c) Dĉe

d) DĉE

e) dCE


Q.9.   Low ionic strength saline is used to:

a) Digest off the sialic residues

b) Increase the surface of shear

c) Decrease the rate of association between the antigen and antibody

d) Remove water molecules from the cell surface

e) Increase the rate of association between the antigen and the antibody


Q.10. The minor cross-match:

a) Tests for antibodies in patient’s serum

b) Tests for antibodies in the donor’s serum

c) Is the commonest compatibility test done

d) Uses 1% of patient’s cells

e) Tests for autoantibodies


Q.11. Rhogam is:

a) Given within 6 days of delivery

b) Given to all Du positive mothers

c) Given to all D-positive mothers

d) Purified incomplete Anti – D

e) Given to the affected baby


Q.12. IgA occurs in the two different forms in the mucous secretions as:

a) Pentamers

b) Polymers

c) Dimers

d) Trimers

e) Monomers


Q.13. The alternative pathway of complement is activated by:

a) An immune complex of IgG and IgM

b) Streptokinase

c) Endotoxins

d) IgE

e) IgD


Q.14. “Neck-lace” pattern type of reaction is characteristic of:

a) Kell typing

b) MNS typing

c) P-system

d) Lewis typing

e) Kidd typing


Q.15. Examples of adjuvants used in the preparation of Coombs serum are:

a) Sodium chloride

b) Sulphuric acids

c) Ammonium nitrate

d) Freud’s adjuvant

e) Ammonium sulphate 4%


Q.16. The placenta plays a very important role such as:

a) Determining the foetal blood group

b) A barrier to a certain class of antibodies

c) Controlling the foetal weight

d) Determining the sex of the baby

e) Nutrients pass through it to the foetus


Q.17. Blood group specific substances are:

a) Glycoproteins

b) Lipopolysaccharide

c) Lipid soluble

d) Water-soluble

e) Found on red blood cells


Q.18. 22% Albumin is prepared from:

a) Guinea pigs

b) Cows

c) Pigs

d) Goats

e) Horses



Q.19. A Secretor must have:

a) h gene

b) ŝeŝe gene

c) H gene

d) Secretor gene

e) An unaltered precursor substance I


Q.20. The antibody causing precipitation is:

a) Present on the red cells

b) Soluble

c) Particulate

d) Precipitinogen

e) Precipitin


Q.21. Sera from patients with paroxysmal cold Haemoglobinuria is associated with:

a) Anti – P

b) Anti – Tja

c) Luke antibody

d) Donath-Landsteiner antibody

e) Anti – Le


Q.22. The following diseases can be transmitted through blood transfusion:

a) Gonorrhoea

b) Viral hepatitis

c) Diabetes

d) Pneumonia

e) HIV


Q.23. Damages to red blood cells during freezing may be prevented by:

a) Rapid freezing

b) Addition of Adenine

c) Rapid thawing

d) Addition of glycerol

e) Removal of plasma


Q.24. The source of enzyme bromelin is:

a) Apple

b) Pawpaw

c) Hog

d) Horse

e) Pineapple


Q.25. The purpose of Exchange transfusion is:

a) To change the baby’s blood group

b) To remove paternal antibody

c) To prevent the formation of Calcium deposits in the brain

d) To lower the bilirubin levels

e) To remove maternal antibody


Q.26. Antibody absorption:

Is the same as antibody adsorption

Is dislodging attached antibody to the cells back to the solution

Is applied in cases of preparation of suitable typing sera

Is the same as inhibition test

Is the removal of unwanted antibody from serum by use of specific cells